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Osimertinib, cyamemazine and lenvatinib added to Possible Risk List

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The safe use of the CredibleMeds® lists of QT-prolonging medications requires awareness of any changes that are made to the lists. Here are the changes made in November and December 2015.

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Prescription medicines cause an estimated 100,000 deaths each year in the US—the fourth leading cause of preventable death. One might ask, since the pharmaceutical industry is required to spend billions of research dollars to generate scientific information on new drugs, how could such harm still occur?

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An innovative and novel concept was described in a recent Commentary in Clinical Pharmacology & Therapeutics, calling for the development and implementation of a potentially transformative medical-decision support technology described as “medication autopilots” by the authors.

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The safe use of the CredibleMeds® lists of QT-prolonging medications requires being aware of any changes that are mede to the lists. Therefore, we wish to inform you of the following changes.

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Changes made to classification of some antidepressants

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Donepezil and cilostazol added to the list of of drugs with Known Risk of TdP. Torsemide added to the list of drugs with Conditional Risk of TdP. Atomoxetine added to the list of drugs with Possible Risk of TdP.

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Fosphenytoin removed from two lists, Ciprofloxacin and Fluconazole moved to Known Risk of TdP list, and Propofol added to the list of drugs with Known Risk of TdP.

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