Resources for Healthcare Professionals

This section of CredibleMeds® includes tools to assist physicians, nurses, pharmacists and other healthcare professionals who play central roles in medication safety.

QT Drugs List:  This portal includes QTdrugs.org, a list of drugs categorized by their potential to cause QT prolongation and/or torsades de pointes (TdP).  Click on a drug and see if the FDA-approved label mentions contraindicated concomitant meds or recommends ECG monitoring. 

Categories of TdP risk for drugs on the QTdrugs List:

Drugs with known risk of TdP

Drugs with possible risk of TdP

Drugs with conditional risk of TdP - i.e., drugs that can cause TdP under certain conditions or which create conditions that foster TdP

 

Additional drug information is provided when you click on a drug name: 

1. Information on routes of administration associated with QT/TdP risk..
2. PubMed Links:  Automatically search the National Library of Medicine's PubMed databease for articles on the drug's ability to prolong the QT interval and/or cause torsades de pointes (TdP).
3. FDA label:  Information on whether the drug's label includes a "black box" warning for QT/arrhythmia, mentions QT prolongation or TdP, mentions contraindicated concomitant drugs or recommends ECG monitoring.

Drugs can be displayed by TdP risk category and sorted by: Generic Name, Brand Name, Risk Category, Pharmacologic Class, and Therapeutic Use.

List of Drugs to be Avoided (DTA) in patients with congenital Long QT: DTA List includes all drugs on the QTdrugs List plus drugs with Special Risk due to their adrenergic actions.A printable pdf of the DTA List can be exported by all registered users.

QTFactors.org - Clinical Factors Associated with Prolonged QTc and/or TdP: This is a list of clinical factors or conditions that have been associated with prolonged QTc and/or Torsades de Pointes (TdP) in the scientific literature.

OncoSupport™ Drug List:  This is a printable list of the drugs that are on the QTdrugs List and which are often prescribed for patients with cancer. It includes designation of each drug's TdP risk category.

 Clinical Aids:

Clinical criteria for classification of cases of drug-induced Long QT and/or torsades de pointes.

A pocket summary of the clinical effects of antiarrhythmc drugs and their actions on the ECG, ion channels and membrane receptors.  Contributed by Romero, K and Woosley, RL, Chapter 18, Clinical Pharmacology of Antiarrhythmic Drugs, Cardiovascular Therapeutics:  A Companion to Braunwald's Heart Disease, Fourth Edition edited by E.M. Antman and M.S. Sabatine, 2012. 

Click here to print a PDF.