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Recent changes to QTdrugs lists and new drug search function

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The safe use of the CredibleMeds® lists of medications requires that the user have the most up-to-date versions. Therefore, we wish to inform you of the following changes to the lists on the website: Fluvoxamine (brand names Faverin®, Fevarin®, Floxyfral®, Dumyrox® and Luvox®), a drug used to treat obsessive-compulsive disorder and other psychiatric illnesses, has been added to the list of drugs with Conditional Risk of torsades de pointes (TdP). Its use has been associated with TdP under certain conditions, especially when used in excessive doses or with drugs that prolong the QT interval. Amphotericin B (brand names Fungilin®, Fungizone®, Abelcet®, AmBisome®, Fungisome®, Amphocil®, Amphotec®) is an antifungal drug found to be associated with TdP under certain conditions, especially when used with drugs that prolong the QT interval, when it has induced hypokalemia or when given by rapid infusion. Therefore, it has also been added to the Conditional Risk list. The antipsychotic zotepine (brand names Losizopilon®, Lodopin®, Setous® and Zoleptil®) has been added to the list of drugs with Possible Risk of TdP. Another antipsychotic, sultopride (brand names Barnotil®, Topral®, Barnetil®), a drug marketed in Asia and some European countries, has been added to the list of drugs with Known Risk of TdP.

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The Sudden Arrhythmic Death Syndromes (SADS) Foundation is hosting its annual conference in San Diego from September 30 through October 2nd.

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The safe use of the CredibleMeds® lists ...

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Ranolazine moved to Conditional Risk of TdP list

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These drugs have been added to the QTdrugs lists.

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To reduce the costs of medicines safely…

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Drs. Peter Schwartz and Ray Woosley publish review: Predicting the Unpredictable - Drug-induced QT Prolongation and TdP

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Ezogabine added to Possible Risk list and Atazanavir moved to Known Risk List

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CredibleMeds® places drugs into broad categories based on whether each can cause QT prolongation or TdP and does not rank-order them by relative risk.

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