New Drugs (Propafenone, tramadol, metolazone) Added to QTdrugs Lists on CredibleMeds®

March 01, 2018 at 7:05 PM

March 1, 2018

We wish to inform all that we have added the following  three drugs to the QTdrugs lists.

Tramadol, a medicine for pain, has been added to the Possible Risk of Torsades de Pointes (TdP) category due to evidence that it is associated with QT prolongation when taken at clinically recommended doses.

 Propafenone, a medicine used to treat heart rhythm disturbances, and Metolazone, a diuretic, have been added to the Conditional Risk list because they have been associated with TdP under certain conditions.




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Posted by Dcollins on
Thank you for this update that you have added Tramadol to the list. I think other drugs should be added like Fentanyl, hydromorphine, Morphine, etc.

Donna Collins, Canada
Opiate researcher
Posted by Suzieqtk on
Thank you for updating this. I had Tramadol in the past. I felt horrible. Now I know why! It's a never ending cycle. Best thing is to never put anything except your betas in your mouth (or proven safe)!! :)
Posted by rwoosley on
Thanks for your suggestion. We follow these drugs closely and have not found convincing evidence that meeting the standard we have set for each list (See ADECA process). If you have evidence that we might have missed, we would be grateful if you could share it with us. Ray Woosley, AZCERT
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